BDBM50001652 6-[4-(4-Amino-phenyl)-6-phenyl-pyridin-2-yloxy]-2,2-dimethyl-hexanoic acid::CHEMBL137104

SMILES CC(C)(CCCCOc1cc(cc(n1)-c1ccccc1)-c1ccc(N)cc1)C(O)=O

InChI Key InChIKey=XGOACMYASLFVJL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001652   

TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001652(CHEMBL137104 | 6-[4-(4-Amino-phenyl)-6-phenyl-pyri...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001652(CHEMBL137104 | 6-[4-(4-Amino-phenyl)-6-phenyl-pyri...)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001652(CHEMBL137104 | 6-[4-(4-Amino-phenyl)-6-phenyl-pyri...)
Affinity DataIC50: 15nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed