BDBM50001660 2-Methyl-6-(6-phenyl-4-p-tolyl-pyridin-2-yloxy)-hexanoic acid::CHEMBL137089

SMILES CC(CCCCOc1cc(cc(n1)-c1ccccc1)-c1ccc(C)cc1)C(O)=O

InChI Key InChIKey=ISBLSCGDCSQHLM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001660   

TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001660(CHEMBL137089 | 2-Methyl-6-(6-phenyl-4-p-tolyl-pyri...)
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001660(CHEMBL137089 | 2-Methyl-6-(6-phenyl-4-p-tolyl-pyri...)
Affinity DataIC50: 30nMAssay Description:Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001660(CHEMBL137089 | 2-Methyl-6-(6-phenyl-4-p-tolyl-pyri...)
Affinity DataIC50: 570nMAssay Description:Inhibition of LTB4-induced elastase release in human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed