BDBM50001669 7-(4,6-Diphenyl-pyridin-2-yloxy)-heptanoic acid::CHEMBL135434

SMILES OC(=O)CCCCCCOc1cc(cc(n1)-c1ccccc1)-c1ccccc1

InChI Key InChIKey=QRYVOEGOCVLABL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001669   

TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001669(CHEMBL135434 | 7-(4,6-Diphenyl-pyridin-2-yloxy)-he...)
Affinity DataIC50: 15nMAssay Description:Inhibition of [3H]-LTB4 binding to Leukotriene B4 receptor in the human polymorphonuclear leukocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001669(CHEMBL135434 | 7-(4,6-Diphenyl-pyridin-2-yloxy)-he...)
Affinity DataIC50: 25nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Centre De Recherche De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50001669(CHEMBL135434 | 7-(4,6-Diphenyl-pyridin-2-yloxy)-he...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of [3H]LTB4 binding to Leukotriene B4 receptor in the guinea pig spleen membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed