BDBM50003123 1-[3-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-[1,2,4]thiadiazol-5-yl]-2-methyl-isothiourea; hydrochloride::CHEMBL543650

SMILES CSC(N)=Nc1nc(ns1)-c1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI Key InChIKey=IGHWEOXHRGFHKR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50003123   

TargetProstaglandin G/H synthase 1/2(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50003123(CHEMBL543650 | 1-[3-(3,5-Di-tert-butyl-4-hydroxy-p...)
Affinity DataIC50: 170nMAssay Description:Evaluated in vitro for its inhibitory activity against Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50003123(CHEMBL543650 | 1-[3-(3,5-Di-tert-butyl-4-hydroxy-p...)
Affinity DataIC50: 1.20E+3nMAssay Description:Evaluated in vitro for its inhibitory activity against 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed