BDBM50003126 4-(5-Amino-[1,2,4]thiadiazol-3-yl)-2,6-di-tert-butyl-phenol::CHEMBL17091

SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)-c1nsc(N)n1

InChI Key InChIKey=HYHIPGJKSYRVCB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50003126   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50003126(CHEMBL17091 | 4-(5-Amino-[1,2,4]thiadiazol-3-yl)-2...)
Affinity DataIC50: 330nMAssay Description:Evaluated in vitro for its inhibitory activity against 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50003126(CHEMBL17091 | 4-(5-Amino-[1,2,4]thiadiazol-3-yl)-2...)
Affinity DataIC50: 2.20E+3nMAssay Description:Evaluated in vitro for its inhibitory activity against Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50003126(CHEMBL17091 | 4-(5-Amino-[1,2,4]thiadiazol-3-yl)-2...)
Affinity DataIC50: 2.00E+4nMAssay Description:IC50 value against ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50003126(CHEMBL17091 | 4-(5-Amino-[1,2,4]thiadiazol-3-yl)-2...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed