BDBM50003315 CHEMBL421247::[5-Benzyl-17-(3-guanidino-propyl)-4,7,10,13,16,19-hexaoxo-icosahydro-3a,6,9,12,15,18-hexaaza-cyclopentacyclooctadecen-11-yl]-acetic acidcyclo(Pro-Arg-Gly-Asp-Gly-D-Phe)

SMILES NC(=N)NCCC[C@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](CC(O)=O)NC(=O)CNC1=O

InChI Key InChIKey=ZIIFEZWMXHWZIY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50003315   

TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003315(CHEMBL421247 | [5-Benzyl-17-(3-guanidino-propyl)-4...)
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50003315(CHEMBL421247 | [5-Benzyl-17-(3-guanidino-propyl)-4...)
Affinity DataKi:  1.85E+4nMAssay Description:Inhibition of [3H]Mba-(N-Me)Arg-Gly-Asp-Man binding to GPIIb/IIIa from human platelets reconstituted in liposomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed