BDBM50003815 CHEMBL3235321

SMILES CC1(C)Oc2nc(C(F)(F)F)nc(N)c2N=C1c1ccc2c(c1)CC[C@]21CC[C@@H](CC(=O)O)CC1

InChI Key InChIKey=YFJNLPDVCDNOMJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50003815   

TargetDiacylglycerol O-acyltransferase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003815BDBM50003815(CHEMBL3235321)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003815BDBM50003815(CHEMBL3235321)
Affinity DataIC50: 4nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003815BDBM50003815(CHEMBL3235321)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells using [14C]palmitoyl CoA as substrate after 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003815BDBM50003815(CHEMBL3235321)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human liver flag-tagged DGAT2 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetSterol O-acyltransferase 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50003815BDBM50003815(CHEMBL3235321)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full-length flag-tagged ACAT2 expressed in baculovirus infected insect cells using [14C]palmitoyl CoA as substrate after 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed