BDBM50005319 6-Cyclohexyl-5-{2-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionylamino]-hexanoylamino}-4-hydroxy-2-isopropyl-hexanoic acid butylamide;0.8H2O::CHEMBL348921

SMILES CCCCNC(=O)[C@@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](CCCC)NC(=O)C(Cc1ccccc1)N1C(=O)c2ccccc2C1=O)C(C)C

InChI Key InChIKey=QPYAWSUMHUMYIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005319   

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005319(CHEMBL348921 | 6-Cyclohexyl-5-{2-[2-(1,3-dioxo-1,3...)
Affinity DataIC50: 87nMpH: 7.4Assay Description:Compound was evaluated for the inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed