BDBM50005320 6-Cyclohexyl-5-{2-[4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-oxo-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl]-hexanoylamino}-4-hydroxy-2-isopropyl-hexanoic acid butylamide;0.7H2O::CHEMBL165476

SMILES CCCCNC(=O)[C@@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](CCCC)N1Cc2ccccc2C[C@H](N2C(=O)c3ccccc3C2=O)C1=O)C(C)C

InChI Key InChIKey=MMNICBAGYUSAOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005320   

TargetRenin(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005320(CHEMBL165476 | 6-Cyclohexyl-5-{2-[4-(1,3-dioxo-1,3...)
Affinity DataIC50: 2.00E+4nMpH: 7.4Assay Description:Compound was evaluated for the inhibition of human plasma renin at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed