BDBM50006215 (1'R,2'S,3'R)-9-(2',3'-dihydroxycyclopent-4'-enyl)adenine::(1S,2R,5R)-5-(6-Amino-purin-9-yl)-cyclopent-3-ene-1,2-diol::5-(6-Amino-purin-9-yl)-cyclopent-3-ene-1,2-diol::CHEMBL299961
SMILES Nc1ncnc2n(cnc12)[C@@H]1C=C[C@@H](O)[C@H]1O
InChI Key InChIKey=RQPALADHFYHEHK-JKMUOGBPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50006215
Affinity DataKi: 41nMAssay Description:Time course of inactivation of bovine liver S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Inhibitory activity of the compound against bovine liver S-adenosyl-L-homocysteine hydrolase (AdoHcy).More data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+3nMAssay Description:In vitro inhibitory activity of the compound against recombinant S-adenosyl-L-homocysteine hydrolase obtained from human placentaMore data for this Ligand-Target Pair
Affinity DataIC50: 877nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.13E+3nMAssay Description:Inhibition of recombinant human AHCY using SAH as substrate assessed as formation of homocysteine after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.83E+3nMAssay Description:Inhibition of human placental AdoHcy hydrolase expressed in Escherichia coli JM109More data for this Ligand-Target Pair