BDBM50006820 2-[3-(1H-Tetrazol-5-ylmethyl)-phenoxymethyl]-quinoline::CHEMBL81199

SMILES C(Oc1cccc(Cc2nnn[nH]2)c1)c1ccc2ccccc2n1

InChI Key InChIKey=PQCFEOVZOWBTSB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50006820   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006820(CHEMBL81199 | 2-[3-(1H-Tetrazol-5-ylmethyl)-phenox...)
Affinity DataIC50: 3.90E+3nMAssay Description:Concentration that produces 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006820(CHEMBL81199 | 2-[3-(1H-Tetrazol-5-ylmethyl)-phenox...)
Affinity DataIC50: 6.20E+3nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase receptor in rat polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006820(CHEMBL81199 | 2-[3-(1H-Tetrazol-5-ylmethyl)-phenox...)
Affinity DataIC50: 1.34E+4nMAssay Description:The compound was tested for inhibitory activity against Prostaglandin G/H synthase in rat polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed