BDBM50006847 CHEMBL86374::N-[2-(2-Amino-thiazol-4-yl)-1-(1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-ethyl]-2-(morpholine-4-sulfonylamino)-3-phenyl-propionamide

SMILES CC(C)C[C@H](O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@@H](Cc1csc(N)n1)NC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)N1CCOCC1

InChI Key InChIKey=QGJKHQRFJGLJLV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50006847   

TargetRenin(Human)
Parke-Davis Pharmaceutical Research Division of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006847(CHEMBL86374 | N-[2-(2-Amino-thiazol-4-yl)-1-(1-cyc...)
Affinity DataIC50: 33nMAssay Description:Compound was evaluated for inhibition of plasma renin activity in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Parke-Davis Pharmaceutical Research Division of Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50006847(CHEMBL86374 | N-[2-(2-Amino-thiazol-4-yl)-1-(1-cyc...)
Affinity DataIC50: 1.45E+4nMAssay Description:Compound was evaluated for the percent inhibition of Cathepsin D in BovineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed