BDBM50007190 CHEMBL3237589

SMILES CCn1c2ccccc2c2cc(Nc3ccnc(NCCCN4CCOCC4)n3)ccc12

InChI Key InChIKey=AFTZZRFCMOAFCR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50007190   

TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007190(CHEMBL3237589)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Rac1 in human MDA-MB-435 cells after 24 hrs by G-LISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007190(CHEMBL3237589)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Vav2 binding to Rac1 G15A mutant in human MDA-MB-231 cells after 1 hr by pull down assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007190(CHEMBL3237589)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Rac1 in human MDA-MB-231 cells assessed as reduction in Rac-GTP level after 24 hrs by ELISA-based pull down assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007190(CHEMBL3237589)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Rac1 in human MDA-MB-435 cells assessed as reduction in Rac-GTP level after 24 hrs by ELISA-based pull down assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed