BDBM50008160 (1-{1-[1-Cyclohexylmethyl-3,3-difluoro-3-(2-morpholin-4-yl-ethylcarbamoyl)-2-oxo-propylcarbamoyl]-but-3-enylcarbamoyl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester::CHEMBL262385

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC=C)C(=O)N[C@@H](CC1CCCCC1)C(=O)C(F)(F)C(=O)NCCN1CCOCC1

InChI Key InChIKey=JPMKMPAXJXWYBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008160   

TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008160(CHEMBL262385 | (1-{1-[1-Cyclohexylmethyl-3,3-diflu...)
Affinity DataIC50: 3.60nMAssay Description:The concentration producing 50% inhibition of renin activity in monkey plasma was determined by radioimmunoassay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50008160(CHEMBL262385 | (1-{1-[1-Cyclohexylmethyl-3,3-diflu...)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibitory activity against bovine Cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed