BDBM50008436 CHEMBL141013::{3-[(2-Bromo-5-trifluoromethyl-phenylthiocarbamoyl)-methyl]-4-oxo-3,4-dihydro-phthalazin-1-yl}-acetic acid

SMILES OC(=O)Cc1nn(CC(=S)Nc2cc(ccc2Br)C(F)(F)F)c(=O)c2ccccc12

InChI Key InChIKey=NWZJXNAKOKFTDF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008436   

TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50008436(CHEMBL141013 | {3-[(2-Bromo-5-trifluoromethyl-phen...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory activity against aldose reductase isolated from human placentaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed