BDBM50008856 2-Methyl-acenaphthene-1-carboxylic acid methyl-(7-pyrrolidin-1-yl-1-oxa-spiro[4.5]dec-8-yl)-amide; hydrochloride::CHEMBL544276

SMILES CC1C(C(=O)N(C)[C@H]2CCC3(CCCO3)C[C@@H]2N2CCCC2)c2cccc3cccc1c23

InChI Key InChIKey=XWROGPXUCYJQLL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008856   

TargetKappa-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008856(CHEMBL544276 | 2-Methyl-acenaphthene-1-carboxylic ...)
Affinity DataKi:  0.370nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008856(CHEMBL544276 | 2-Methyl-acenaphthene-1-carboxylic ...)
Affinity DataKi:  244nMAssay Description:Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008856(CHEMBL544276 | 2-Methyl-acenaphthene-1-carboxylic ...)
Affinity DataKi:  578nMAssay Description:Compound was evaluated for the opioid receptor delta affinityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed