BDBM50008857 CHEMBL543329::N-Methyl-2-naphthalen-1-yl-N-(7-pyrrolidin-1-yl-1-oxa-spiro[4.5]dec-8-yl)-acetamide; hydrochloride

SMILES CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1cccc2ccccc12

InChI Key InChIKey=FOQROCUUQJEYDF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008857   

TargetKappa-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008857(CHEMBL543329 | N-Methyl-2-naphthalen-1-yl-N-(7-pyr...)
Affinity DataKi:  3.40nMAssay Description:Compound was evaluated for Opioid receptor kappa 1 affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008857(CHEMBL543329 | N-Methyl-2-naphthalen-1-yl-N-(7-pyr...)
Affinity DataKi:  864nMAssay Description:Compound was evaluated for the Opioid receptor mu 1 affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed