BDBM50008986 2-(1-Naphthalen-1-yl-ethyl)-1,2-dihydro-indazol-3-one::CHEMBL3144575

SMILES C[C@H](c1cccc2ccccc12)n1[nH]c2ccccc2c1=O

InChI Key InChIKey=AOOSKFQNKDXJCS-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008986   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008986(2-(1-Naphthalen-1-yl-ethyl)-1,2-dihydro-indazol-3-...)
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro inhibition of LTB4 production was measured in rat bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008986(2-(1-Naphthalen-1-yl-ethyl)-1,2-dihydro-indazol-3-...)
Affinity DataEC50: >3.46E+5nMAssay Description:Ex vivo inhibition of LTB4 production was measured in dog bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008986(2-(1-Naphthalen-1-yl-ethyl)-1,2-dihydro-indazol-3-...)
Affinity DataIC50: 4.00E+5nMAssay Description:In vitro inhibition of PGE-2 production was measured in rat bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed