BDBM50009901 6-(3-Methyl-thioureido)-2-(3-naphthalen-1-yl-2-naphthalen-1-ylmethyl-propionylamino)-hexanoic acid {4-[2-(2-amino-ethyl)-morpholin-4-yl]-2-hydroxy-1-isobutyl-4-oxo-butyl}-amide::CHEMBL281134

SMILES CNC(=S)NCCCCC(NC(=O)C(Cc1cccc2ccccc12)Cc1cccc2ccccc12)C(=O)NC(CC(C)C)[C@@H](O)CC(=O)N1CCOC(CCN)C1

InChI Key InChIKey=QJWWZBWMLPVXMI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009901   

TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009901BDBM50009901(CHEMBL281134 | 6-(3-Methyl-thioureido)-2-(3-naphth...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009901BDBM50009901(CHEMBL281134 | 6-(3-Methyl-thioureido)-2-(3-naphth...)
Affinity DataIC50: 125nMAssay Description:Inhibitory activity against monkey plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009901BDBM50009901(CHEMBL281134 | 6-(3-Methyl-thioureido)-2-(3-naphth...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibitory activity against bovine Cathepsin D was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed