BDBM50011045 6-{2-[6-Chloro-4-(4-fluoro-phenyl)-2-methyl-quinolin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL334113

SMILES Cc1nc2ccc(Cl)cc2c(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1

InChI Key InChIKey=WRMOSELMQIYDOA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011045   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011045(CHEMBL334113 | 6-{2-[6-Chloro-4-(4-fluoro-phenyl)-...)
Affinity DataIC50: 720nMAssay Description:Compound was evaluated for the inhibition of HMG-CoA reductase (COR) in rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed