BDBM50011224 8-Dicyclopropylmethyl-2,6-dioxo-1,3-dipropyl-1,2,3,6-tetrahydro-purine-7-carboxylic acid methyl ester::CHEMBL358971

SMILES CCCn1c2nc(C(C3CC3)C3CC3)n(C(=O)OC)c2c(=O)n(CCC)c1=O

InChI Key InChIKey=NRKQQIAUTZNVFE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011224   

TargetAdenosine receptor A1(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50011224(CHEMBL358971 | 8-Dicyclopropylmethyl-2,6-dioxo-1,3...)
Affinity DataKi:  6.90E+3nMAssay Description:Inhibition of [3H]cyclohexyladenosine binding to guinea pig forebrain membranes adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50011224(CHEMBL358971 | 8-Dicyclopropylmethyl-2,6-dioxo-1,3...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity carried out with [3H]5'-(N-ethylcarbamoyl)-adenosine in the presence of 50 nM cyclopentyladenosine in rat striatal membranes against...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed