BDBM50012617 CHEMBL3260841

SMILES CO[C@H]1CCC2(Cc3ccc(cc3C22N=C(N)N(C)C2=O)-c2cccc(c2)C#N)CC1

InChI Key InChIKey=CQCYWEAFJHYRMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012617   

TargetBeta-secretase 1(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50012617(CHEMBL3260841)
Affinity DataIC50: 4nMAssay Description:Inhibition of myc-his-tagged BACE ectodomain (1 to 454) secreted from HEK293 cells using Cy3-SEVNLDAEFK-Cy5Q-NH2 as substrate measured for 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed