BDBM50012646 CHEMBL3261056

SMILES [H][C@@]12COC[C@@]1(N=C(N)N(C)S2(=O)=O)c1cc(NC(=O)c2cnc(cn2)C(F)F)ccc1F

InChI Key InChIKey=IQUBPELHSBAKON-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012646   

TargetBeta-secretase 2(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50012646(CHEMBL3261056)
Affinity DataKi:  17nMAssay Description:Inhibition of human BACE2 catalytic domain using QSY7-EISEVNLDAEFC-Eu-amide as substrate preincubated for 30 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50012646(CHEMBL3261056)
Affinity DataKi:  27nMAssay Description:Inhibition of recombinant soluble human BACE1 catalytic domain using QSY7-EISEVNLDAEFC-Europium-amide as substrate preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed