BDBM50012650 CHEMBL3261064

SMILES NC1=N[C@@](CF)(COC1)c1cccc(NC(=O)c2ccc(Cl)cn2)c1

InChI Key InChIKey=KEFNSMANAYXFOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012650   

TargetBeta-secretase 1(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50012650(CHEMBL3261064)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human BACE1 extracellular domain expressed in baculovirus using fluorescence-quenched peptide substrate derived from APP se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed