BDBM50012661 CHEMBL3261079

SMILES C[C@]1(CS(=O)(=O)C2(CCCCC2)C(N)=N1)c1cc(NC(=O)c2ccc(Cl)cn2)ccc1F

InChI Key InChIKey=QTKARDGAUMDUCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012661   

TargetBeta-secretase 1(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50012661(CHEMBL3261079)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of recombinant soluble human BACE1 catalytic domain using QSY7-EISEVNLDAEFC-Europium-amide as substrate preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed