BDBM50012789 2,6-Di-tert-butyl-4-(2-pyridin-3-yl-vinyl)-phenol::CHEMBL414824

SMILES CC(C)(C)c1cc(\C=C\c2cccnc2)cc(c1O)C(C)(C)C

InChI Key InChIKey=LMLDPXXCYIXDSG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50012789   

TargetProstaglandin G/H synthase 1/2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012789(CHEMBL414824 | 2,6-Di-tert-butyl-4-(2-pyridin-3-yl...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012789(CHEMBL414824 | 2,6-Di-tert-butyl-4-(2-pyridin-3-yl...)
Affinity DataIC50: 670nMAssay Description:Inhibitory concentration required for inhibition of Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2019
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012789(CHEMBL414824 | 2,6-Di-tert-butyl-4-(2-pyridin-3-yl...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed