BDBM50012987 6-(2-Hydroxy-ethyl)-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrochloride::CHEMBL553060

SMILES OCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31

InChI Key InChIKey=SWOYTIGXQORDEW-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50012987   

TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50012987(CHEMBL553060 | 6-(2-Hydroxy-ethyl)-5,6,6a,7-tetrah...)
Affinity DataKi:  13nMAssay Description:Agonist activity was tested in vitro against Dopamine receptor from rat brain membranes with [3H]ADT-6,7-dihydroxy-2-aminotetralin]More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50012987(CHEMBL553060 | 6-(2-Hydroxy-ethyl)-5,6,6a,7-tetrah...)
Affinity DataIC50: 25nMAssay Description:Inhibition of [3H]apomorphine binding to calf caudate membrane preparation (p4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2018
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50012987(CHEMBL553060 | 6-(2-Hydroxy-ethyl)-5,6,6a,7-tetrah...)
Affinity DataKi:  1.46E+3nMAssay Description:Dopamine receptor D2 affinity was tested in vitro against corpus striatum from rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50012987(CHEMBL553060 | 6-(2-Hydroxy-ethyl)-5,6,6a,7-tetrah...)
Affinity DataKi: >1.00E+4nMAssay Description:Dopamine receptor D1 affinity was tested in vitro against corpus striatum from rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed