BDBM50013273 CHEMBL3262652

SMILES Cc1cnc(c(C)c1)-c1cc(ncc1Cl)N1CCn2cc(NC(=O)C(F)(F)F)nc2C1

InChI Key InChIKey=AFXGOPWFLDYHAG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50013273   

TargetSmoothened homolog(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50013273(CHEMBL3262652)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Smo receptor (unknown origin) expressed in NIH3T3 cells assessed as inhibition of Smo agonist SAG-induced GRE activation after 30 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed