BDBM50013625 22-cyclopropylmethyl-11-methyl-(1S,2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol::22-cyclopropylmethyl-11-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl2H2O)::22-cyclopropylmethyl-11-methyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol

SMILES Cn1c2[C@@H]3Oc4c5c(CC6N(CC7CC7)CC[C@@]35[C@@]6(O)Cc2c2ccccc12)ccc4O

InChI Key InChIKey=CRTCCMARDBQOKA-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50013625   

TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50013625(22-cyclopropylmethyl-11-methyl-(2S,13R)-14-oxa-11,...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity was measured by the displacement of [3H]- DADLE in guinea pig brain membrane of opioid receptor deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50013625(22-cyclopropylmethyl-11-methyl-(2S,13R)-14-oxa-11,...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity was measured by the displacement of [3H]- DADLE in guinea pig brain membrane of Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50013625(22-cyclopropylmethyl-11-methyl-(2S,13R)-14-oxa-11,...)
Affinity DataKi:  14nMAssay Description:Binding affinity was measured by the displacement of [3H]- DAMGO in guinea pig brain membrane of opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50013625(22-cyclopropylmethyl-11-methyl-(2S,13R)-14-oxa-11,...)
Affinity DataKi:  14nMAssay Description:Binding affinity was measured by the displacement of [3H]- DAMGO in guinea pig brain membrane of Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50013625(22-cyclopropylmethyl-11-methyl-(2S,13R)-14-oxa-11,...)
Affinity DataKi:  65nMAssay Description:Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of opioid receptor kappaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50013625(22-cyclopropylmethyl-11-methyl-(2S,13R)-14-oxa-11,...)
Affinity DataKi:  65nMAssay Description:Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed