BDBM50014706 2-{4-[2-(2,4-Diamino-pteridin-6-yl)-butyl]-benzoylamino}-pentanedioic acid::CHEMBL302068
SMILES CCC(Cc1ccc(cc1)C(=O)NC(CCC(O)=O)C(O)=O)c1cnc2nc(N)nc(N)c2n1
InChI Key InChIKey=BRBJBKGSGUBGLP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50014706
Affinity DataKi: 0.00550nMAssay Description:Concentration of the compound inhibiting Dihydrofolate reductase derived from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.20E+3nMAssay Description:Inhibitory activity towards Dihydrofolate reductase derived from human manca leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Binding affinity of the compound towards Dihydrofolate reductase derived from L1210 cells using [3H]- MTX as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration of the compound inhibiting thymidylate synthase enzyme of L. caseiMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Concentration of the compound inhibiting AICAR formyltransferase enzyme of L. caseiMore data for this Ligand-Target Pair