BDBM50014949 4-Hydroxy-6-[2-(2,4,6-trichloro-naphthalen-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL424166

SMILES O[C@@H]1CC(CCc2c(Cl)cc(Cl)c3cc(Cl)ccc23)OC(=O)C1

InChI Key InChIKey=ZWTXDHXYESDLCS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50014949   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014949(CHEMBL424166 | 4-Hydroxy-6-[2-(2,4,6-trichloro-nap...)
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed