BDBM50015427 CHEMBL3265017
SMILES COc1ccc(Nc2nc(cn3ccnc23)-c2ccc3cn[nH]c3c2)cc1OC
InChI Key InChIKey=YRFUVUYUKBPPHG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50015427
Affinity DataIC50: 3.80nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 919nMAssay Description:Inhibition of Syk in goat antihuman IgE-induced CD63 expression in human whole blood by FACS analysisMore data for this Ligand-Target Pair
Affinity DataKd: 9nMAssay Description:Binding affinity to Syk (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Inhibition of Syk in antihuman IgM-stimulated human Ramos cells assessed as decrease in BCR-mediated BLNK phosphorylation by cellular assayMore data for this Ligand-Target Pair