BDBM50016217 CHEMBL3262163

SMILES Cl.COc1ccc(NC(=O)N2CCNC[C@@H]2COc2cccnc2)cc1

InChI Key InChIKey=GYVJDAOHVCIKJN-XFULWGLBSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50016217   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Critical Therapeutics

Curated by ChEMBL
LigandPNGBDBM50016217(CHEMBL3262163)
Affinity DataIC50:  19nMAssay Description:Inhibition of biotinylated alpha-bungarotoxin binding to alpha7 nAChR in rat PC12 cells by FACS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Critical Therapeutics

Curated by ChEMBL
LigandPNGBDBM50016217(CHEMBL3262163)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of human ERG by whole-cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Critical Therapeutics

Curated by ChEMBL
LigandPNGBDBM50016217(CHEMBL3262163)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Critical Therapeutics

Curated by ChEMBL
LigandPNGBDBM50016217(CHEMBL3262163)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Critical Therapeutics

Curated by ChEMBL
LigandPNGBDBM50016217(CHEMBL3262163)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Critical Therapeutics

Curated by ChEMBL
LigandPNGBDBM50016217(CHEMBL3262163)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Critical Therapeutics

Curated by ChEMBL
LigandPNGBDBM50016217(CHEMBL3262163)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed