BDBM50016733 8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine::CHEMBL26688

SMILES COc1cccc2CCC(N)Cc12

InChI Key InChIKey=RVKOHSCTEHZRRT-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50016733   

Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016733(CHEMBL26688 | 8-Methoxy-1,2,3,4-tetrahydro-naphtha...)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016733(CHEMBL26688 | 8-Methoxy-1,2,3,4-tetrahydro-naphtha...)
Affinity DataKi:  53nMAssay Description:Binding affinity at [3H]8-OH-DPAT-Labeled 5-hydroxytryptamine 1A receptor sites in rat brain hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016733(CHEMBL26688 | 8-Methoxy-1,2,3,4-tetrahydro-naphtha...)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50016733(CHEMBL26688 | 8-Methoxy-1,2,3,4-tetrahydro-naphtha...)
Affinity DataKi:  178nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50016733(CHEMBL26688 | 8-Methoxy-1,2,3,4-tetrahydro-naphtha...)
Affinity DataKi:  902nMAssay Description:Binding affinity against 5-hydroxytryptamine 1B receptor in rat striatal membranes using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50016733(CHEMBL26688 | 8-Methoxy-1,2,3,4-tetrahydro-naphtha...)
Affinity DataKi:  1.44E+5nMAssay Description:The compound was tested for In vitro inhibitory activity against Phenylethanolamine N-Methyltransferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed