BDBM50016767 2-[1-(2-Carboxy-2-hydroxy-ethylcarbamoyl)-2-phenyl-ethylamino]-4-phenyl-butyric acid::CHEMBL165617

SMILES O[C@@H](CNC(=O)[C@H](Cc1ccccc1)N[C@@H](CCc1ccccc1)C(O)=O)C(O)=O

InChI Key InChIKey=QAQRHURCJWHRJU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50016767   

TargetNeprilysin(Rabbit)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50016767(CHEMBL165617 | 2-[1-(2-Carboxy-2-hydroxy-ethylcarb...)
Affinity DataIC50: 11nMAssay Description:Compound was evaluated for the ability to inhibit neutral endopeptidase purified from rabbit kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Rabbit)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50016767(CHEMBL165617 | 2-[1-(2-Carboxy-2-hydroxy-ethylcarb...)
Affinity DataIC50: 11nMAssay Description:Compound was evaluated for the ability to inhibit neutral endopeptidase purified from rabbit kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rat)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50016767(CHEMBL165617 | 2-[1-(2-Carboxy-2-hydroxy-ethylcarb...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for the ability to inhibit Angiotensin I converting enzyme in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rat)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50016767(CHEMBL165617 | 2-[1-(2-Carboxy-2-hydroxy-ethylcarb...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for the ability to inhibit Angiotensin I converting enzyme in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed