BDBM50017060 CHEMBL553991::N-Methyl-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-4-trifluoromethyl-benzamide; hydrochloride

SMILES CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=HUFBLXFPRKMQOF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017060   

TargetMu-type opioid receptor(Guinea pig)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017060(CHEMBL553991 | N-Methyl-N-(1-methyl-1-aza-spiro[4....)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against opioid receptor mu of guinea pig brain using [3H]DAGO radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017060(CHEMBL553991 | N-Methyl-N-(1-methyl-1-aza-spiro[4....)
Affinity DataIC50: 670nMAssay Description:Binding inhibition against Opioid receptor kappa 1 of guinea pig was determined using [3H]ethylketocyclazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50017060(CHEMBL553991 | N-Methyl-N-(1-methyl-1-aza-spiro[4....)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against Opioid receptor delta 1 of guinea pig was determined by using [3H]DADLE radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed