BDBM50017086 CHEMBL3287052::US9428504, 79

SMILES COC(=O)c1ccc(O)c2N(CC3(CCN(CC(C)(C)C)CC3)c12)c1ccccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=BEVLLXJNRJKQHJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017086   

TargetP2Y purinoceptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50017086(CHEMBL3287052 | US9428504, 79)
Affinity DataIC50: 0.150nMAssay Description:Antagonist activity at P2Y1 receptor in human platelets by FLIPR assay in presence of 2-methylthio-ADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50017086(CHEMBL3287052 | US9428504, 79)
Affinity DataKi:  9nM ΔG°:  -11.0kcal/molepH: 7.4 T: 2°CAssay Description:A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent