BDBM50017097 1-Benzoyl-4-(3,4-dimethoxy-phenyl)-pyrrolidin-2-one::CHEMBL287311
SMILES COc1ccc(cc1OC)C1CN(C(=O)c2ccccc2)C(=O)C1
InChI Key InChIKey=HFUCOPVFORARRN-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50017097
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of cGMP-PDE phosphodiesterase from bovine aorta using 1 uM cGMP (insignificant)More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B(Bos taurus)
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of phosphodiesterase from bovine aorta with 1 uM cGMP calcium (10 uM) and calmodulin (15 nM) (insignificant)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cAMP for cAMP-PDE.More data for this Ligand-Target Pair