BDBM50017112 1-Acetyl-4-(3,4-dimethoxy-phenyl)-pyrrolidin-2-one::CHEMBL32727

SMILES COc1ccc(cc1OC)C1CN(C(C)=O)C(=O)C1

InChI Key InChIKey=IZTABMWLNKLGJV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017112   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50017112(1-Acetyl-4-(3,4-dimethoxy-phenyl)-pyrrolidin-2-one...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of cGMP-PDE phosphodiesterase from bovine aorta using 1 uM cGMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50017112(1-Acetyl-4-(3,4-dimethoxy-phenyl)-pyrrolidin-2-one...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cAMP for cAMP-PDE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017112(1-Acetyl-4-(3,4-dimethoxy-phenyl)-pyrrolidin-2-one...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against cAMP phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cGMP in the presence of calcium (10 uM) and ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed