BDBM50017113 4-(3,4-Dimethoxy-phenyl)-1-phenyl-pyrrolidin-2-one::CHEMBL284845

SMILES COc1ccc(cc1OC)C1CN(C(=O)C1)c1ccccc1

InChI Key InChIKey=XDGPXVGLRZEIGQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50017113   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50017113(4-(3,4-Dimethoxy-phenyl)-1-phenyl-pyrrolidin-2-one...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cAMP for cAMP-PDE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50017113(4-(3,4-Dimethoxy-phenyl)-1-phenyl-pyrrolidin-2-one...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of cGMP-PDE phosphodiesterase from bovine aorta using 1 uM cGMP (insignificant)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed