BDBM50017114 4-[4-Methoxy-3-(2-methyl-allyloxy)-phenyl]-pyrrolidin-2-one::CHEMBL439920

SMILES COc1ccc(cc1OCC(C)=C)C1CNC(=O)C1

InChI Key InChIKey=KVRMWFVMLVTJIA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017114   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50017114(4-[4-Methoxy-3-(2-methyl-allyloxy)-phenyl]-pyrroli...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cGMP for cGMP-PDE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017114(4-[4-Methoxy-3-(2-methyl-allyloxy)-phenyl]-pyrroli...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cGMP in the presence of calcium (10 uM) and calmodu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50017114(4-[4-Methoxy-3-(2-methyl-allyloxy)-phenyl]-pyrroli...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cAMP for cAMP-PDE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed