BDBM50017121 4-(4-Butoxy-phenyl)-pyrrolidin-2-one::CHEMBL32597

SMILES CCCCOc1ccc(cc1)C1CNC(=O)C1

InChI Key InChIKey=CAECIASHQVBHQZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50017121   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50017121(4-(4-Butoxy-phenyl)-pyrrolidin-2-one | CHEMBL32597)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cGMP for cGMP-PDE;Compound is insignificant.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50017121(4-(4-Butoxy-phenyl)-pyrrolidin-2-one | CHEMBL32597)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against cAMP phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cGMP in the presence of calcium (10 uM) and ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50017121(4-(4-Butoxy-phenyl)-pyrrolidin-2-one | CHEMBL32597)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of cAMP-PDE phosphodiesterase from bovine aorta using 1 uM cAMP (insignificant)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed