BDBM50018229 2-(4-Hydroxy-phenyl)-2-phenyl-propionic acid 2-diethylamino-ethyl ester::CHEMBL37372
SMILES CCN(CC)CCOC(=O)C(C)(c1ccccc1)c1ccc(O)cc1
InChI Key InChIKey=WFXACEPWPCLBGC-UHFFFAOYSA-N
Data 7 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50018229
TargetMuscarinic acetylcholine receptor M2(Human)
Walter Reed Army Institute of Research
Curated by ChEMBL
Walter Reed Army Institute of Research
Curated by ChEMBL
Affinity DataKi: 0.165nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M2 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Human)
Walter Reed Army Institute of Research
Curated by ChEMBL
Walter Reed Army Institute of Research
Curated by ChEMBL
Affinity DataKi: 0.881nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M1 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of carbachol-induced release of alpha-amylase from pancreatic acinar cells from that of rat ileum contained the M2 receptor subtypesMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Human)
Walter Reed Army Institute of Research
Curated by ChEMBL
Walter Reed Army Institute of Research
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M1 receptor after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Human)
Walter Reed Army Institute of Research
Curated by ChEMBL
Walter Reed Army Institute of Research
Curated by ChEMBL
Affinity DataKi: 52.2nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M3 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of [3H]NMS binding to cerebral cortex membranes which contain predominantly the Muscarinic acetylcholine receptor M1 subtypesMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Human)
Walter Reed Army Institute of Research
Curated by ChEMBL
Walter Reed Army Institute of Research
Curated by ChEMBL
Affinity DataKi: 566nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M4 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair