BDBM50018419 CHEMBL27762::[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetic acid ethyl ester::[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)-phenoxy]-acetic acid ethyl ester

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(OCC(=O)OCC)cc1

InChI Key InChIKey=MVDJCRHMFYMNMB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50018419   

TargetAdenosine receptor A2a/A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50018419([4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-p...)
Affinity DataKi:  30nMAssay Description:Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50018419([4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-p...)
Affinity DataKi:  42nMAssay Description:Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes with 1 nM [3H]cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50018419([4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-p...)
Affinity DataKi:  42nMAssay Description:Inhibition of 1 nM [3H]N-6-(phenylisopropyl)adenosine binding to A1 receptors in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Niddk

Curated by ChEMBL
LigandPNGBDBM50018419([4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-p...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of binding of [3H]5'-(N-ethylcarbamoyl)-adenosine to adenosine A2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed