BDBM50018533 CHEMBL3290668

SMILES Nc1ncc(F)c2n(cnc12)[C@@H]1C(F)C[C@@H](O)[C@H]1O

InChI Key InChIKey=OSSJTLZIFDTAEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50018533   

TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018533(CHEMBL3290668)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetAdenosylhomocysteinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50018533(CHEMBL3290668)
Affinity DataIC50: 455nMAssay Description:Inhibition of recombinant human AHCY using SAH as substrate assessed as formation of homocysteine after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed