BDBM50019276 CHEMBL72599::N-[5-(2-Fluoro-phenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-4-methoxy-benzamide

SMILES COc1ccc(cc1)C(=O)NC1N=C(c2ccccc2F)c2ccccc2NC1=O

InChI Key InChIKey=QYWNMRNYQJYZOF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50019276   

TargetCholecystokinin receptor type A(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50019276(CHEMBL72599 | N-[5-(2-Fluoro-phenyl)-2-oxo-2,3-dih...)
Affinity DataIC50: 95.5nMAssay Description:Binding affinity against cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50019276(CHEMBL72599 | N-[5-(2-Fluoro-phenyl)-2-oxo-2,3-dih...)
Affinity DataIC50: 96nMAssay Description:Half-maximal inhibition of [125I]CCK-33 binding to cholecystokinin A receptor from rat pancreatic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019276(CHEMBL72599 | N-[5-(2-Fluoro-phenyl)-2-oxo-2,3-dih...)
Affinity DataIC50: 5.40E+3nMAssay Description:Half-maximal inhibition of [125I]gastrin binding to guinea pig gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019276(CHEMBL72599 | N-[5-(2-Fluoro-phenyl)-2-oxo-2,3-dih...)
Affinity DataIC50: 4.00E+4nMAssay Description:Half-maximal inhibition of [125I]-CCK-8(+) binding to cholecystokinin receptor from guinea pig brain tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed