BDBM50019691 CHEMBL3286565

SMILES CNc1nc(nc2CCNCCc12)C(C)c1ccccc1

InChI Key InChIKey=RNJKYOKEWFJMSB-UHFFFAOYSA-N

Data  2 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50019691   

Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50019691(CHEMBL3286565)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50019691(CHEMBL3286565)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]-mesulergine from human recombinant 5-HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50019691(CHEMBL3286565)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human 5-HT2B receptor expressed in CHO K1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50019691(CHEMBL3286565)
Affinity DataEC50:  112nMAssay Description:Agonist activity at recombinant human 5-HT2C receptor expressed in CHO K1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50019691(CHEMBL3286565)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at recombinant human 5-HT2B receptor expressed in CHO K1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50019691(CHEMBL3286565)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human 5-HT2C receptor expressed in CHO K1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed