BDBM50019901 CHEMBL3287206::US9533999, i-34

SMILES CC(C)c1nc2N(Cc3ccc(F)c(OC(F)(F)F)c3)C(=O)CS(=O)(=O)c2s1

InChI Key InChIKey=ZWDRWONPTSZBKW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019901   

TargetIntermediate conductance calcium-activated potassium channel protein 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50019901(CHEMBL3287206 | US9533999, i-34)
Affinity DataIC50: 96nMAssay Description:HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

TargetIntermediate conductance calcium-activated potassium channel protein 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50019901(CHEMBL3287206 | US9533999, i-34)
Affinity DataIC50: 96nMAssay Description:Inhibition of human KCa3.1 overexpressed in HEK293 cells assessed as thallium influx preincubated for 15 mins followed by thallium/ionomycin addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed