BDBM50020412 CHEMBL3289811

SMILES Nc1nc2ccc(OC3CCOC3)nc2n1CC(O)c1ccc(cc1Cl)C(F)(F)F

InChI Key InChIKey=QAKLYMPRDNHSCY-UHFFFAOYSA-N

Data  6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50020412   

TargetCytochrome P450 2C19(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50020412(CHEMBL3289811)Copy SMILESCopy InChI

Affinity DataIC50: 780nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/11/2015
Entry Details Article
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TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50020412(CHEMBL3289811)Copy SMILESCopy InChI

Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/11/2015
Entry Details Article
Copy Entry DOIPubMed
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TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50020412(CHEMBL3289811)Copy SMILESCopy InChI

Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/11/2015
Entry Details Article
Copy Entry DOIPubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50020412(CHEMBL3289811)Copy SMILESCopy InChI

Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/11/2015
Entry Details Article
Copy Entry DOIPubMed
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TargetCytochrome P450 1A2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50020412(CHEMBL3289811)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/11/2015
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetCytochrome P450 2C9(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50020412(CHEMBL3289811)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/11/2015
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL