BDBM50020578 1-[2-(4-Azido-3-iodo-phenyl)-ethyl]-4-(3-trifluoromethyl-phenyl)-piperazine::CHEMBL155615

SMILES FC(F)(F)c1cccc(c1)N1CCN(CCc2ccc(N=[N+]=[N-])c(I)c2)CC1

InChI Key InChIKey=DGGQFCKCVDYJDO-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50020578   

Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020578(CHEMBL155615 | 1-[2-(4-Azido-3-iodo-phenyl)-ethyl]...)
Affinity DataKi:  18nMAssay Description:In vitro inhibition of [3H]5-HT (2 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020578(CHEMBL155615 | 1-[2-(4-Azido-3-iodo-phenyl)-ethyl]...)
Affinity DataKi:  20nMAssay Description:In vitro inhibition of [3H]DPAT (1 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020578(CHEMBL155615 | 1-[2-(4-Azido-3-iodo-phenyl)-ethyl]...)
Affinity DataIC50: 35nMAssay Description:In vitro inhibition of [3H]5-HT (2 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020578(CHEMBL155615 | 1-[2-(4-Azido-3-iodo-phenyl)-ethyl]...)
Affinity DataIC50: 41nMAssay Description:In vitro inhibition of [3H]5-HT (2 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed